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Genome wide association studies identified an increasing number of common variants associated with these diseases

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The nuclear localization signal (NLS) (residues 617633) is localized at the junction between the DBD and the hinge region (residues 624665) and is responsible for nuclear import of the receptor 50,51

10.1016/j.psj.2020.01.024 Poult Sci

Feasibility of adjunct therapeutic hypothermia treatment for hyperammonemia and encephalopathy due to urea cycle disorders and organic acidemias

It supplies the acetyl group for burning fats in mitochondria (fatty acid oxidation) and producing acetylcholine