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Description
Selective NNMT Inhibitors Improve Metabolic Function in Experimental Models

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5-Amino-1MQs membrane-permeable small-molecule structure produces oral bioavailability in rodent models, distinguishing it from peptide compounds and supporting the oral capsule research format

Of note, ABHD5 can bind multiple PNPLA family members (37, 70-72), suggesting that it functions as scaffold for forming various enzymatic assemblies, or metabolons, to mediate a wide array of metabolic processes

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