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10.1126/science.1059501

High-power magnification usually shows a lentiginous and nested proliferation of nevomelanocytes but often spindle or epithelioid forms

For persistent freckles, treatments like laser therapy, topical creams, or chemical peels are usually needed to achieve visible lightening

Dermatoscopy is a principal tool for clinical assessment of skin lesions and should be used routinely for all skin lesions
