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Intranasal GHK-Cu treatment had a nonsignificant suppressive effect on microglia in males but not females as demonstrated by staining intensities of IBA-1 (Figure 4B)

This peptidergic drugs multimodal action has sustained scientific interest despite mixed clinical trial results, particularly in acute ischemic stroke and neurodegenerative disease research

doi: 10.3389/fcvm.2024.1446468 Received 09 June 2024 Accepted 21 November 2024 Published 16 December 2024 Volume 11 - 2024 Edited by Masanori Aikawa, Brigham and Women's Hospital and Harvard Medical School, United States Reviewed by Prabhash Kumar Jha, Brigham and Women's Hospital and Harvard Medical School, United States Satyesh K

28 (10), E578 (2013)