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Iron depletion is a novel therapeutic strategy to target cancer stem cells

Excessive reduction of ROS may impair these fundamental physiological functions, potentially weakening host defense mechanisms and disrupting normal skin repair processes

In addition, except for anti-malaria drugs, menin-mixed-lineage leukemia (MLL) inhibitors used to treat MLL-rearranged leukemia were also reported able to exert an excellent cytotoxic effect on EOC cells via inducing ferroptosis [44]
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Mechanistic studies suggest that organ-specific delivery patterns and the in vivo fate of ZP-LNPs are largely governed by pKa values and the composition of the protein corona

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