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Bioavailability remains a major translational challenge for oral curcumin, which undergoes rapid metabolism and shows limited systemic exposure unless delivered through optimized formulations (e.g., liposomes, nano-phytosomes)

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A unifying concept across dietary interventions in PCOS is the focus on anti-inflammatory, nutrient-dense, and sustainable dietary patterns rather than restrictive caloric approaches alone [416]

Body weight loss, muscle wasting, anorexia and inflammation are the four key characteristics of cancer cachexia
Di Vincenzo F, Del Gaudio A, Petito V, Lopetuso LR, Scaldaferri F
