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Description
Compared with bacterial CGS, plant CGS have an N-terminal extension (amino acids 77-87) that displays a regulatory role ( Nicotiana tabacum transgenic plants highlighted both a strongly altered development and an impaired Met metabolism
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Arch Toxicol 2016
As a hypoxia-inducible transmembrane glycoprotein, CAIX catalyzes the rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions, helping to maintain acidification of the tumor microenvironment and enhance resistance to cytotoxic therapy in some hypoxic tumors
doi: 10.1016/j.ymthe.2021.09.015