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Recent studies further demonstrate that vascular regression and impaired angiogenesis within the corpus luteum are strongly associated with hypoxia-driven ROS accumulation and subsequent luteal insufficiency [44]

In the brain, millimolar concentrations of GSH are present within the cells (Dringen 2000), while extracellular GSH concentrations in the brain are orders of magnitude lower (Hilgier et al

[3] Despite also being antibiotics, macrolides exert immunomodulatory effects on the host inflammatory response without systemic suppression of the immune system

The keywords used were nano and responsive, combined with the International Patent Classification (IPC) to focus on the biomedical field, specifically IPC classification numbers A61P, A61K, C07K, C07H, C12N, C12Q, and G01N (e.g., A61K stands for specific preparations for medical, dental, or toiletry purposes)

The inhaled tacrolimus (Tac, 60 g/mouse) albumin NPs revealed significant anti-fibrotic efficiency in mice with bleomycin-induced PF, which was much better than the effectiveness resulting from intraperitoneal administration of Tac based on histopathological results (Seo et al., 2016)

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