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As stated in an article in Scientific American on the lack of racial and ethnic diversity in clinical trials, if diverse groups arent part of these studies, we cant be sure whether the treatment will work in all populations or what side effects might emerge in one group or another. Historically, minority groups and women have been underrepresented in medical studies

[2] Useful metabolites are excluded since they are polar, and in general contain one or more charged groups

Another important aspect of this study is that the downregulation of mGluR8 in neuroblastoma SH-SY5Y could be important to study the mechanism of chemoresistance to the treatment with a chemotherapeutic agent

As a cofactor for enzymatic reactions, it participates in DNA synthesis and repair, part of cellular maintenance

Aliyu M, Zohora FT, Anka AU, Ali K, Maleknia S, Saffarioun M, et al

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