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Description
Especially in UPR, although TMAO can selectively activate PERK-mediated UPR by binding to PERK, this does not explain TMAO-mediated aggregation of unfold or misfolded proteins in AD
The MS model of EAE suggests that SCFAs may contribute to the onset and progression of the disease in mice

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doi: 10.1023/A:1018874300026 76 LeungCRiveraLFurnessJBAngusPW

2022;465 doi: 10.1016/j.tox.2021.153043
