glutathione degradation ferroptosis L-2-Hydroxyglutarate sensitizes through ATF3/CHAC1-mediated in hepatocellular carcinoma GSH and Ferroptosis: Side-by-Side Partners

Oh S, Kim SH, Ko Y, et al

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This selective interference targets cells that have accumulated stress-related damage while sparing healthy cells

This indicates that ferroptosis is essential for health maintenance via regulating metabolic and redox balance, as well as being implicated in the development and treatment of multiple human diseases 12,13,14 (Fig

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Elevated insulin levels directly suppress AOD-9604's lipolytic activity