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Furthermore, APOE4-targeted replacement mice, carrying the human APOE4 allele (a known strong risk factor for developing late-onset AD), display significant depressive-like behaviors compared to APOE3 counterparts, especially under stress conditions (Fang et al., 2021
doi: 10.1158/2159-8290.CD-20-0119
Sind zu wenige davon vorhanden, wird die Darmschleimhaut in ihrer Struktur und Funktion beeintrchtigt
Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload

Wu K, Wang X, Xie Z, Liu Z, Lu Y
Primary Handling Editor: George Inglis