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The quadriceps are often stronger than the hamstrings, which can create an imbalance that increases the strain on the ACL during activities

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Very rarely, more serious reactions can occur, such as a severe allergic reaction

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Initially described in Japan over a century ago as a pronounced lymphoid goitre predominantly affecting women, nowadays, not only is HT recognized as the most common cause of hypothyroidism but also as the most common autoimmune and endocrine disease (4)

In fetal congenital disorders, in utero delivery can be a valuable option for gene delivery (Swingle et al., 2022