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doi: 10.1038/mt.2011.164

16 AML is a prime example in which the capacity to self-renew is tested in xenotransplantation assays where LSC engraft in immune-deficient recipient mice giving rise to leukemia

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Whether releasing immunosuppression could facilitate the clearance of ferroptosis-associated pathogenic signals is an emerging research direction (Hu and Weiner, 2024