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[4] The process according to claim 1 or 2, wherein the enzyme is lipase, esterase or protease having a hydrolytic capacity, which is used directly or is immobilized prior to use

It helped prevent mental decline related to aging in animal studies

However, the importance for the HCV genotyping may decline with the availability of highly and broadly effective all oral combination therapies in the future

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As for targeted therapy in cancer metabolism, gain of function mutations in isocitrate dehydrogenases (IDH1 and IDH2) result in the production of the oncometabolite 2-hydroxyglutarate (140, 141)