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In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]

Randomized controlled trials of the treatment of lumbar disk herniation: 19832007

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On PND 7, pups were treated orally with curcumin at 1 g/kg, and analyses were performed on whole-brain homogenates collected at day 28