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Herrero-Mendez et al., 2009)

Enzymatic assessments revealed that THC treatment led to a reduction in the levels of matrix metalloproteinases 2 and 9 (MMP-2, MMP-9), as well as urokinase plasminogen activator (uPA)
This complex activates the mitogen activated protein kinase (MAP kinase) pathway

Stemmer A, Margalit O, Serpas V, Strauss G, Thomas J, Shah P, Tau N, Levanon K, Shacham-Shmueli E, Kopetz S , Overman M, Boursi B

Gil Romero J

Any disruption of this stabilityincluding reduced bile salt secretion or altered phospholipid concentrationscan result in the precipitation of bilirubin
