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2023), and CD38 deficiency has been demonstrated to improve steatosis and oxidative stress in HFD-fed mice with MASLD (Xiao et al

Nolla, University of Barcelona, Spain The article belongs to the special issue Complementary and Integrative Medicine in Rheumatology: Evidence, Therapies, and Clinical Impact Antioxidant and anti-inflammatory compound whose biological properties have been linked to modulation of oxidative stress, cytokine signaling, and bone metabolism

Itaconate is a dicarboxylic acid that is produced from the TCA cycle intermediate, cis -aconitate, by the enzyme aconitate decarboxylase 1 which is encoded by the ACOD1 gene

A few studies have also highlighted the role of bacterial, fungal, or viral infection in OSF

Craig et al

K.IslamA.ZhuS.ElhassanA.MohammedA.WinbladB.et al (2004)
