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[132] [143] [153] Sufficiently overexpressing JunD in the nucleus accumbens with viral vectors can completely block many of the neural and behavioral alterations seen in chronic drug abuse (i.e., the alterations mediated by FosB)

Diagnosis is clinical (ie, there is no single confirmatory lab test) and is often delayed

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10.1093/eurheartj/ehy799 80 WangZ.KlipfellE.BennettB

Carnitine homeostasis does not consist of the simple maintenance of constant carnitine concentration

(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)