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In fact, when we studied cold response in BAT and iWAT in untreated mice, we also found that Ckb is upregulated (Extended Data Fig

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Interestingly, the turning point in the GSH level timecourse of females (age 45) is within the period of menopause

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doi: 10.3389/fphar.2026.1761748 Received 05 December 2025 Revised 25 March 2026 Accepted 01 April 2026 Published 22 April 2026 Volume 17 - 2026 Edited by Ming Xu, Shimonoseki City University, Japan Reviewed by Gaetano De Siena, University of Florence, Italy Wei Guo, University of North Carolina at Greensboro, United States Updates Copyright 2026 Nandagopal and Manickam