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Indeed, PPs affect the cancerous cells gene expression profile, leading to suppressing cancerous cell development and metastasis (389, 390)

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13 , 14 For example, metabolites like hypoxanthine, an ATP-breakdown and oxidation product, have been correlated to hemolysis and post-transfusion recoveries in mice and humans

Therefore, when modulating the gut microbiota to alter SCFA levels, it is crucial to simultaneously consider their bioavailability at both the local intestinal and systemic levels to avoid the metabolic burden caused by excess energy

Durand, M

These features are typically bilateral and symmetrical, with preservation of dermal thickness and echogenicity