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Description
They function primarily during mammalian development to establish DNA methylation patterns as epigenetic remodeling and reprogramming proceed during differentiation
Experiments were carried out at the temperatures given in the procedures
The receptor was originally isolated from a human gastric tumor cell line and contains a chain of 50 kDa and a chain of 145 kDa which are linked with disulphide bridges in a transmembrane complex of 190 kDa
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ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling
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