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Key biochemical markers, such as alanine aminotransferase (ALT), total bilirubin (TBIL), aspartate aminotransferase (AST), and albumin (ALB), are widely used to reflect liver function

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N., & Khavinson, V

Cole GM, Morihara T, Lim GP, Yang F, Begum A, Frautschy SA

The genetic mutation responsible for that disorder causes cystine to accumulate within cellular lysosomes (5860)

Parallel mechanisms underlying CUD and/or psychosis Recent clinical data now show that individuals with first-episode psychosis with a comorbid CUD have increased neuromelanin (a proxy for dopamine) in psychosis-associated midbrain dopaminergic nuclei, which scaled with CUD severity [6]