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Serious events (organ toxicity, hormone suppression) have not been documented, but long-term safety data are lacking

Corticotropin-Releasing Hormone and Brain Mast Cells Regulate Blood-Brain-Barrier Permeability Induced by Acute Stress

[DOI] [Google Scholar] Cesarec V, Becejac T, Misic M, et al

10.1111/apt.12147 281

W., Dorrell, C

Long-term nasal spray use carries theoretical concerns about mucosal damage
