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Food Science & Nutrition, 6 (8), 24462458

203 Sugar and Calories Multiple studies have implicated high-sugar and high-calorie diets with the development of NAFLD

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Presumably, the dry skin results from normalization of differentiation and proliferation of the keratinocytes and loosening of their adhesion to one another, thereby resulting in flaky skin.[25] One can also speculate that a topical retinoid would also bind to the sebocytes retinoid receptors, resulting in decreased sebum production, but evidence has yet to exclusively illustrate that topical retinoids are sebosuppressive.[26] Both tazarotene and tretinoin have been reported to reduce facial pore size