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Although the modulation of transcription through histone modification serves as a useful paradigm, the mechanisms that mediate the anticancer effects of HDIs are more complex, with many non-histone targets identified (Figure 2)

Int J Reprod Biomed

Cell Stem Cell 3 : 391401

The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation