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Elevated norepinephrine can induce vasoconstriction through -adrenergic receptor activation in both testicular and penile vasculature, thereby compromising testicular perfusion and opposing the smooth muscle relaxation required for erection (128, 129)

These studies have suggested that there may be mechanisms beyond antioxidant activities playing a neuroprotective role [118]

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Acta Diabetol 55(4):341353 Singh B, Kumar A, Singh H, Kaur S, Arora S, Singh B (2022) Protective effect of vanillic acid against diabetes and diabetic nephropathy by attenuating oxidative stress and upregulation of NF-B, TNF- and COX-2 proteins in rats

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