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The high toxicity of H 2 O 2 can be easily explained by its chemical nature: it has no unpaired electrons and possesses a relatively long half-time (1 ms), so it is able to cross biological membranes and to diffuse across long distances, increasing the number of potential sites of action (Gupta et al

Other sulfur rich foods include: meat, eggs, and fish grains, including rice, bread, and pasta vegetables, such as onion, garlic, broccoli, kale, and cabbage According to a 2013 pilot study, one 250-gram portion of steamed broccoli increased the activity of the enzyme glutathione Stransferase, suggesting increased plasma levels of glutathione, and improved oxidative stress resistance in 10 healthy adult males who smoked

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In parallel, delivery technologies such as recombinant protein formulations, exosome purification and focused ultrasound should be evaluated in animal models [307, 308]

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