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PMCID: PMC7569385.

This allows for deeper tissue imaging and improved visualization of cancer cells in vivo

4-HNE in high concentrations is one of the most toxic and mutagenic metabolites of lipid peroxidation for the cell (Nicolaou et al., 2010

In order to become accessible to Trx/Grx, one of the hairpins must hinge open, to allow Trx/Grx to dock in place of the strand

Interestingly, RipAYs enzymatic activity requires the activation by eukaryotic thioredoxins, which are highly abundant in plants during pathogen infection (Tada et al., 2008)

Despite the lack of conclusive evidence on the benefits of early detection of recurrence, the Panel identified consistent general post-RC follow-up strategies amongst urologist members of the EAU Bladder Cancer Guidelines Panels and developed a practice-based framework guided by expert opinion (Table 7.1) [458]