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Moreover, MMP-1 synthesis activates the degradation of collagen produced by fibroblasts, resulting in wrinkles on the surface of human skin [48]

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Consistent with the observation in peripheral tissues such as the adipose tissue, chronic glargine-induced nuclear localization of HIF1 in conjunction with nuclear monomeric PKM2, which facilitated a robust nuclear HRE binding in the central nervous system (i.e., cerebellum and cerebral cortex) (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Raizner A.E

Overexpression of SlLTPG3 resulted in increased cuticular wax and cutin accumulation, leading to delayed fruit softening and an extended shelf life in tomatoes compared to wild-type plants (Wang et al., 2022)
