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In support of this hypothesis, metformin enhanced the anti-tumor effects of figitumumab in SCLC and NSCLC cell lines

P2RX7 is unique among purinergic receptors since it is involved in mechanisms of neuroinflammation and is responsible for ATP-dependent cell lysis (Falzone et al., 2018)

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Images shown are representative of triplicate slides ran on at least three sets of animals with each set consisting of a Sham, TBI, and TBI+ICAL mouse