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Additional side effects that may occur with injectable B12 include a headache and feelings of pins and needles, says Drugs.com

Why Vitamin B12 Deficiency Is Often Missed in Aging Adults Vitamin B12 deficiency is often missed because the symptoms fatigue, anemia, neuropathy, memory problems, or walking difficulties are quite common in older adults, and can easily be caused by something else

Melanin, the pigment responsible for skin colour, is synthesized by melanocytes in the skin

Increased MMA levels cause demyelinating defects in the nervous system and elevate propionic acid, resulting in metabolic acidosis

Nature New Biology , 243(124), 8587

And, because elevated levels of stress can weaken the immune system, it can also increase the risk of developing shingles and allow the virus to reactivate