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Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid

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A similar inhibition of NF-B nuclear localization was observed under heat shock conditions in human respiratory epithelial cells (43 C for 24 h), followed by IL-1 or TNF stimulation (1 U/mL for 18 hours), in rat pancreatic islet cells (42 C for 60 min) stimulated with IL-1, and in human pancreatic islet cells (42 C for 90 min) stimulated by IL-1 and IFN (Scarim et al., 1998