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Lett Appl Microbiol 66:416426

Glutathione is an antioxidant tripeptide found in nearly all eukaryotes that results from cysteine, glycine, and glutamic acid [1]

Several promising compounds have failed in clinical trials due to a range of challenges, including inadequate disease models, late intervention timing, insufficient biomarker validation, and difficulty in distinguishing symptomatic from neuroprotective effects

This balance is critical for normal cellular processes and signaling

Furthermore, all randomised controlled trials included in the NMA were identified in an SLR to ensure that all available evidence was considered

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