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Specifically, resveratrol regulates the JAML/SIRT1 lipid synthesis pathway through elevating the SIRT1 expression to reduce the expressions of SREBP-1 and ChREBP protein, further mitigating lipid deposition mediated by SREBP-1 and ChREBP, improving renal pathology and renal function in DKD patients and HFD-induced DKD mice (Gu et al., 2022)

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Effect of saffron on thymocyte proliferation, intracellular glutathione levels and its antitumor activity

10.3389/fnins.2023.1115242 60 HuoJ.XueY.DongX.LvJ.WuL.GaoH.et al (2023)

Cancer onset correlates with age, and senescence plays a role at multiple stages during cancer development

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