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2 ALS Genetics While only a minority of patients with ALS harbor a monogenic cause, the downstream consequences of genetic mutations in patients with ALS have improved mechanistic insights

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However, the researchers the trial was marked as completed, but in 2016 they cancelled submission of the results never published the results This is a red flag: we dont know if an issue or toxicity was discovered, or if it was simply a business decision

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mEPSC amplitude distributions were similarly diminished by acivicin, and more so by MeAIB, although combinations of acivicin and MeAIB did not further impair the effect of MeAIB alone (Fig

[DOI] [PubMed] [Google Scholar] Giannini E