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Divalent cations, including Co 2+ , Ni 2+ , and Zn 2+ , have the capacity to replace Mg 2+ in ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO), leading to its inactivation (Aponte et al

This would explain the particular vascular effect and recovery [1,2,3,4,5,6,7,8,9,10] that may take part in eye and glaucoma therapy, as evidenced by particular effects on NO-agents in eye studies [11,12,13,14,15,16,17]

Srivastava, S

This likely reflects a combination of factors

MEDICC Rev 22:4047

A conceptual summary of the multi-level consequences of heat stress is presented in Figure 1 , illustrating how elevated environmental temperatures initiate a cascade of disruptions from whole-animal health and pathogen dynamics to immune function and cellular responses