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A comparative genomic hybridization, a reciprocal microduplication, and a unique, recurring microdeletion carry a significant risk of autism and are be responsible for around 1% of cases (Weiss et al., 2008)

Sometimes, the shadows may appear mildly dark, while at other times, they form noticeable big black circles around the eyes

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Overall, results indicate that physical disruption of the disc matrix can lead to focal swelling, GAG loss, disturbed cell-matrix binding, cell clustering, and a degenerative cell phenotype

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