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Acknowledgements This study was supported by the grants from Guangdong international cooperation program (2012B050700019) and Guangzhou Enter Nutr Bioscience Co., Ltd

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Some research suggests that diet modifications might help alleviate gut issues and improve behavioral outcomes, though obesity and nutrient deficiencies remain concerns

Initially, we used fivefold cross-validation to determine the best regularization parameter lambda (from 100 values ranging from 10 3 to 10 5 ) for predicting circulating TMAO in the left-out group

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