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Avoid use with drugs that also increase the QT interval and in patients with risk factors for prolonged QT interval ( 5.3) Orthostatic Hypotension and Syncope: Warn patients of risk and symptoms of hypotension ( 5.4)

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While some trials suggest a connection, more peer review is required to confirm whether oral vitamin B12 supplements or intramuscular injections can prevent fractures

Injections bypass the gut and correct deficiency

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