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In a notable phase II clinical trial published in The Lancet (2008), Tesofensine demonstrated dose-dependent weight loss of up to 10.6% over 24 weeks in obese individualssubstantially higher than placebo or many existing weight-loss drugs

After 14 days of administration of different natural products or vehicle, blood samples were collected for hematological and serum biochemical analyses

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10.1016/S0165-5728(98)00168-4 111 HoekR