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Persons affected by major depressive disorder manifested acetyl-l-carnitine deficiency compared to age- and sex-matched healthy individuals in two independent study centres

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[DOI] [PubMed] [Google Scholar] 4.Heart Disease and Stroke Statistics-2020 Update: a report from the American Heart Association

Insulin stimulates l-carnitine accumulation in human skeletal muscle

Carnitine/acetylcarnitine also have potentially positive effects on hormonal and metabolic parameters in patients with reproductive dysfunction, such as polycystic ovary syndrome [86, 87], and these effects may involve a series of complex signal transduction pathways to maintain the homeostasis of the endocrine system [88]