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In the hippocampus, adult neurogenesis occurs in the subgranular zone of the dentate gyrus (111, 112) and is a complex process that involves the proliferation of neural stem cells and progenitor cells (Type 2a, 2b and 3 cells) (113115), the differentiation of neuroblasts into granular neurons through the stadium of immature granular neurons (IGNs), and the integration of new neurons into preexisting circuits in the dentate gyrus (116, 117)

An increase in NF-B activity and its target gene expression and a decrease in anti-inflammatory GATA3 and cytokine expression were observed after Compound C or si-Mfn2 application

doi: 10.2337/diacare.28.7.1769

Excessive calorie intake, especially within a Western-style diet, promotes gut dysbiosis, inflammation, and obesity [52]

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