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Efficacy of a glutathione S -transferase -activated prodrug in platinum-resistant ovarian cancer cells

Table 1 Means SEM of the Doppler ultrasound measures of the supra-testicular arteries at the studied time points: just before LC treatment (0 h) and 1, 4, 24, 48, and 168 h post-treatment in Ossimi rams ( n = 15)

[DOI] [PubMed] [Google Scholar] 18.Handwerker HO, Kilo S, Reeh PW

Urinary deoxypyridinoline concentrations and high-sensitivity C-reactive protein (hs-CRP) levels were notably decreased in the FOS and glucomannan groups relative to control subjects

Ultrarapid metabolisers (especially CYP2D6): The drug is cleared too quickly, meaning blood levels may never reach a therapeutic range
