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However, due to a lack of significant data, in Phase 1 and Phase 2 clinical trials, the manufacturer decided to stop further trials

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After incubation on ice for 8 min, the lysates were centrifuged at 13,000 g for 3 min at 4 C

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Although systemic inflammation is known to modulate iron metabolism, such as interleukin-6 (IL-6) stimulating hepcidin synthesis and subsequently downregulating FPN1, this has been observed primarily in hepatic tissues (95)
