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Its not entirely understood how gabapentin works to relieve RLS symptoms, but studies show it to be effective ( In one study, 24 people with RLS were treated with gabapentin or a placebo for six weeks

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10.1038/s41588-023-01397-9 [DOI] [PMC free article] [PubMed] [Google Scholar] 53.Weng C, Gu A, Zhang S et al (2023) Single cell multiomic analysis reveals diabetes-associated -cell heterogeneity driven by HNF1A