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Reproductive Biology and Endocrinology
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MRT involves transferring healthy mitochondria into the oocytes of mothers carrying pathogenic mtDNA mutations, thereby preventing the transmission of the disease
In addition, vitexin significantly reduced hepatic macrophage infiltration, obviously downregulated the mRNA and protein expressions of hepatic SREBP-1c, FAS, ACC, and could significantly inhibit the expressions of TLR4/NF-B signaling in NAFLD mice ( Another metabolite, quercetin is also reported to protect the liver
Severe kidney impairment and food intake can influence the pharmacokinetic parameters of ALA [54, 55]
