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The further impact of miR-133a on osteosarcoma progression in vivo strongly encourages further studies to evaluate whether it could be a new prognostic biomarker and a possible anti-metastatic target for osteosarcoma treatment

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ACTL6A knockdown (KD) via short hairpin RNA (shRNA) transfection exerted a marked negative effect on GC cell proliferation, while overexpression of ACTL6A exerted a positive effect on GC cell proliferation (Fig