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In one clinical trial: GRP was well tolerated in children with ASD Approximately 60% of participants responded positively Improvements were observed in irritability, hyperactivity, and social withdrawal Although further studies are needed, these findings suggest potential interactions between gut peptides and neurological behavior

Neurol Med Chir (Tokyo) (2018) 58(10):40521

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This observation is interesting, as NFB activation is considered antiapoptotic and pro-survival, in part, due to its role in augmenting the expression of IAPs, which attenuate caspase activation

Cutaneous warming promotes sleep onset