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Kanai, Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor

In vivo , Hong et al

Antioxid (Basel Switzerland) 2016, 5(4)

In the KL26401 Phase I/II study, the overall ORR for 43 patients with advanced NSCLC was 40%, while the ORR in the EGFR mutation subgroup (n = 22) reached 55%, significantly higher than the 24% observed in wild-type patients (P = 0.039)

A standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study

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